Low-molecular-weight heparins for managing vaso-occlusive crises in people with sickle cell disease
نویسندگان
چکیده
منابع مشابه
Hyperbaric oxygen therapy for vaso-occlusive crises in nine patients with sickle-cell disease.
INTRODUCTION Vaso-occlusive crisis (VOC) is the most frequent complication of sickle-cell disease and is associated with significant acute bone pain. OBJECTIVE To evaluate the feasibility and efficacy of hyperbaric oxygen therapy (HBOT) for severe VOC. METHODS We report our retrospective experience with HBOT in VOC in nine patients and 15 HBOT sessions. RESULTS All nine patients had recei...
متن کاملA randomized, controlled clinical trial of ketoprofen for sickle-cell disease vaso-occlusive crises in adults.
Vaso-occlusive crisis (VOC) is the primary cause of hospitalization of patients with sickle-cell disease. Treatment mainly consists of intravenous morphine, which has many dose-related side effects. Nonsteroidal antiinflammatory drugs have been proposed to provide pain relief and decrease the need for opioids. Nevertheless, only a few underpowered trials of nonsteroidal antiinflammatory drugs f...
متن کاملScore Predicting Acute Chest Syndrome During Vaso-occlusive Crises in Adult Sickle-cell Disease Patients
BACKGROUND Vaso-occlusive crisis (VOC), hallmark of sickle-cell disease (SCD), is the first cause of patients' Emergency-Room admissions and hospitalizations. Acute chest syndrome (ACS), a life-threatening complication, can occur during VOC, be fatal and prolong hospitalization. No predictive factor identifies VOC patients who will develop secondary ACS. METHODS This prospective, monocenter, ...
متن کاملBreathing patterns during vaso-occlusive crisis of sickle cell disease.
STUDY OBJECTIVES To determine the effect of sickle cell pain and its treatment on patients' breathing patterns, and to compare the effect of thoracic cage pain to pain at other sites. DESIGN Prospective, observational study. SETTING Sickle Cell Center Day Hospital. PATIENTS Twenty-five patients with sickle cell disease admitted to the Sickle Cell Center Day Hospital for treatment of vaso-...
متن کاملThe vaso-occlusive crisis of sickle cell disease.
Sickle cell anaemia was the first molecular disease to be described'; despite intensive study we still do not understand the relations between the clinical picture, the cellular defects, and the molecular make up of any one person. Two recent papers have further elucidated the complex pathophysiology associated with painful crisis, although their implications for treatment are unclear. Clinicia...
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ژورنال
عنوان ژورنال: Cochrane Database of Systematic Reviews
سال: 2015
ISSN: 1465-1858
DOI: 10.1002/14651858.cd010155.pub3